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Trifluoperazine

CAT: 1568-C11410-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:1568-C11410-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
117-89-5
Synonyms
NSC-17474, RP-7623, SKF-5019
SKU
C11410-5mg
Target
Dopamine Receptor
Applications
Neuronal Signaling
Smiles
CN1CCN (CC1) CCCN2C3=CC=CC=C3SC4=C2C=C (C=C4) C (F) (F) F
Molecular Formula
C21H24F3N3S
Additionnal Information
Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.
Storage Conditions
3 years -20°C powder

Chemical Information

Trifluoperazine

Trifluoperazine is a member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. It has a role as a calmodulin antagonist, a phenothiazine antipsychotic drug, a dopaminergic antagonist, an antiemetic, an EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor and an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. It is an organofluorine compound, a member of phenothiazines, a N-alkylpiperazine and a N-methylpiperazine.

CAS Number117-89-5
PubChem CID5566
IUPAC Name10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
Molecular FormulaC21H24F3N3S
Molecular Weight407.5
XLogP5
Topological Polar Surface Area35
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count28
Formal Charge0
Complexity510
SMILES
CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F
InChI
InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3
InChIKey
ZEWQUBUPAILYHI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Trifluoperazine
CAS: 117-89-5
CID: 5566
Formula: C21H24F3N3S
MW: 407.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight407.5
XLogP35
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass407.16430344
Monoisotopic Mass407.16430344
Topological Polar Surface Area35 Ų
Heavy Atom Count28
Formal Charge0
Complexity510
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5759193Trifluoperazine
CS-ED-02084Trifluoperazine D8
HY-B0532S-01Trifluoperazine-d8
T40692-01Trifluoperazine dimaleate
RM-T181202-01Trifluoperazine Sulfoxide
JH912643Trifluoperazine dihydrochloride
AR-T02982-01Trifluoperazine DiHCl
S3201-1gTrifluoperazine 2HCl
CS-O-44414Trifluoperazine Sulfone
HY-B0532BTrifluoperazine (dimaleate)

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