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Lidocaine hydrochloride

CAT: 1568-C10326-01Size: 100 mgDry Ice: YesHazardous: No
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CAT#:1568-C10326-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
73-78-9
Synonyms
Lidocaine HCL, Lidothesin, Lignocaine hydrochloride, Xyloneural
SKU
C10326-100mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN (CC) CC (=O) NC1=C (C=CC=C1C) C.Cl
Molecular Formula
C14H22N2O.HCl
Additionnal Information
Lidocaine hydrochloride (Lidothesin, Lignocaine, Xyloneural) is an inhibitor of epidermal growth factor receptor (EGFR) and has antiproliferative effect on human tongue cancer cells. Lidocaine hydrochloride is a local anesthetic and cardiac depressant used as an antiarrhythmia agent.
Storage Conditions
2 years -80 in solvent

Chemical Information

Lidocaine Hydrochloride

Lidocaine Hydrochloride is the hydrochloride salt form of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.

CAS Number73-78-9
PubChem CID6314
IUPAC Name2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride
Molecular FormulaC14H23ClN2O
Molecular Weight270.80
Topological Polar Surface Area32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Heavy Atom Count18
Formal Charge0
Complexity228
SMILES
CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl
InChI
InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
InChIKey
IYBQHJMYDGVZRY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Lidocaine Hydrochloride
CAS: 73-78-9
CID: 6314
Formula: C14H23ClN2O
MW: 270.80
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.80
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass270.1498911
Monoisotopic Mass270.1498911
Topological Polar Surface Area32.3 Ų
Heavy Atom Count18
Formal Charge0
Complexity228
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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