PF-477736

CAT: 1568-C08953-01Size: 5 mgDry Ice: YesHazardous: No
CAT#:1568-C08953-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
952021-60-2
Synonyms
PF-736, PF-00477736
SKU
C08953-5mg
Target
Chk
Applications
Cell Cycle
Smiles
CN1C=C (C=N1) C2=C3C=NNC (=O) C4=C3C (=CC (=C4) NC (=O) C (C5CCCCC5) N) N2
Molecular Formula
C22H25N7O2
Additionnal Information
PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.
Storage Conditions
2 years -80 in solvent

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