Products for Research Use Only
RegisterLogin

PF-477736 2HCl

CAT: 0931-T202968-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T202968-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1247874-19-6
Bioactivity
PF-477736, also known as PF-00477736, is a potent CHK1 inhibitor with potential to enhance chemotherapy. This compound inhibits CHK1, an ATP-dependent serine/threonine kinase that is a crucial component of the S/G2 checkpoint system for DNA replication monitoring. By bypassing the final checkpoint defenses against DNA damage-induced lethal effects, PF-477736 may improve the antitumor efficacy of various chemotherapeutic agents in tumor cells with inherent checkpoint deficiencies.
Smiles
O=C1C2=C3C(C=NN1)=C(C4=CN(C)N=C4)NC3=CC(NC([C@@H](C5CCCCC5)N)=O)=C2.Cl.Cl
Molecular Formula
C22H27Cl2N7O2
Molecular Weight
492.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T6028-01PF 477736
T28364-01PF-03463275 2HCl
T72226L1-01PF-4348235 2HCl
T70044L-01Sarizotan 2HCl
T11154L-01EG01377 2HCl
T71707L-01Romergoline 2HCl
T25616-01Lanepitant 2HCl
T83979-01Sulcardine 2HCl
T68485-01Apilimod 2HCl
T28994L-01Topixantrone 2HCl

Alternative Products

CatalogName
GTR19241559-01PF-477736 2HCl
BUP17452-01PF-4348235 2HCl
GTR19196763-01PF-03463275 2HCl
B1437-10PF-477736
sc-362781PF 477736

Popular Products