Hydroxychloroquine

CAT: 1568-C03379-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:1568-C03379-01Size:100 mg
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CAS Number
118-42-3
Synonyms
HCQ
SKU
C03379-100mg
Target
Autophagy
Applications
Autophagy
Additionnal Information
Hydroxychloroquine (HCQ) is an antimalarial drug that inhibits autophagy and is used to treat systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) . It exhibits immunomodulatory, antithrombotic, and antiplatelet properties. It inhibits the release endothelin-1, a potent vasoconstrictor, and restores impaired angiogenesis in TNF-α-treated endothelial cells in vitro. It also reduces the production of inflammatory cytokines such as TNF-α, IFN-γ, and IL-6 from peripheral blood mononuclear cells, upregulates IL-10 and decreases platelet aggregation.

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