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Flonoltinib

CAT: 1568-C03307-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C03307-01Size:5 mg
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CAS Number
2387765-27-5
Synonyms
JAK2/FLT3-IN-1
SKU
C03307-5mg
Target
JAK
Applications
Angiogenesis
Additionnal Information
Flonoltinib (JAK2/FLT3-IN-1) is a potent and selective dual inhibitor of JAK2 and FLT3, with IC50 of of 0.8, 1.4, and 15 nM against JAK2, JAK2V617F, and FLT3, respectively, in in vitro kinase assays. It also inhibits cell proliferation and induces G2/M cell cycle arrest and apoptosis in Hemophagocytic Lymphohistiocytosis (HLH) patients' CD8+T cells, CTLL2 cells, and RAW 264.7 cells.

Alternative Products

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HY-130247-01Flonoltinib
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HY-130247CFlonoltinib (sulfate)
T89283-01Flonoltinib maleate
HY-130247A-01Flonoltinib (TFA)
A24219-50Flonoltinib (JAK2/FLT3-IN-1) 50mg
A24219-100Flonoltinib (JAK2/FLT3-IN-1) 100mg
A24219-10Flonoltinib (JAK2/FLT3-IN-1) 10mg
A24219-5Flonoltinib (JAK2/FLT3-IN-1) 5mg

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