Brigimadlin

CAT: 1568-C01703-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:1568-C01703-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2095116-40-6
Synonyms
BI 907828
SKU
C01703-1mg
Target
MDM2/MDMX
Applications
Apoptosis
Additionnal Information
Brigimadlin (BI 907828) is a potent, orally active inhibitor of E3 ubiquitin-protein ligase MDM-2. Brigimadlin inhibits MDM-2's suppression of the tumor suppressor p53. It promotes apoptosis and enhances the transcription of p53 targets such as p21 and PUMA in BT48, BT67, and BT73 cells.

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