Products for Research Use Only
RegisterLogin

CHD1Li 6.11

CAT: 1568-C01503-02Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1568-C01503-02Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2716890-91-2
SKU
C01503-5mg
Smiles
CC1=CC (=NC (=N1) N2CCCC2) NC3=CC=C (NC (=O) CC4=CC (=CS4) Br) C=C3
Additionnal Information
CHD1Li 6.11, a potent oncogenic chromodomain helicase DNA binding protein 1 like (CHD1L) inhibitor and an orally bioavailable antitumor agent, shows the enzymatic inhibition of the catalytic CHD1L (cat-CHD1L) recombinant protein with IC50 of 3.3 μM, and significantly reduces the tumor volume of colorectal cancer (CRC) xenografts generated from isolated quasi mesenchymal cells (M-Phenotype) .
Storage Conditions
3 years -20°C powder

Chemical Information

CHD1Li 6.11
CAS Number2716890-91-2
PubChem CID156868176
IUPAC Name2-(4-bromothiophen-2-yl)-N-[4-[(6-methyl-2-pyrrolidin-1-ylpyrimidin-4-yl)amino]phenyl]acetamide
Molecular FormulaC21H22BrN5OS
Molecular Weight472.4
XLogP4.6
Topological Polar Surface Area98.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count29
Formal Charge0
Complexity541
SMILES
CC1=CC(=NC(=N1)N2CCCC2)NC3=CC=C(C=C3)NC(=O)CC4=CC(=CS4)Br
InChI
InChI=1S/C21H22BrN5OS/c1-14-10-19(26-21(23-14)27-8-2-3-9-27)24-16-4-6-17(7-5-16)25-20(28)12-18-11-15(22)13-29-18/h4-7,10-11,13H,2-3,8-9,12H2,1H3,(H,25,28)(H,23,24,26)
InChIKey
ACDZBXZERLBYOW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of CHD1Li 6.11
CAS: 2716890-91-2
CID: 156868176
Formula: C21H22BrN5OS
MW: 472.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight472.4
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass471.07284
Monoisotopic Mass471.07284
Topological Polar Surface Area98.4 Ų
Heavy Atom Count29
Formal Charge0
Complexity541
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
C15917-25mgPDM-11
C15917PDM-11
C06950-10mM/1mLWNK-IN-11
C01213Compound 11
C14663-25mgCompound 11
C07036-5mgPDM-11
C06950-25mgWNK-IN-11
C07293-5mgDHODH-IN-11
C16006-25mgDHODH-IN-11
C16006DHODH-IN-11

Alternative Products

CatalogName
T63049-01CHD1Li 6.11
T74370-01CDK4/6-IN-11
GTR19186942-0111β-HSD1-IN-6
sc-133251Int-6 (A-11)
sc-65887TSG-6 (A6.6.11)
0097486,11-Dihydro-11-hydroxy Dothiepin
C4050-1006α-methyl-11β-Hydroxyprogesterone
FS109599-01Substance P (6-11)
HY-116786-0111-Hydroxycanthin-6-one
439154-016α-Hydroxy-11-deoxycortisol

Popular Products