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CHD1Li 6.11

CAT: 0931-T63049-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T63049-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2716890-91-2
Target
Others, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Purity
0.9904
Bioactivity
CHD1Li 6.11 is a potent inhibitor of oncogenic CHD1L, acting on the cat-CHD1L recombinant protein (IC50: 3.3 μM) . CHD1Li 6.11 is an orally active antitumour agent that significantly reduces the tumour volume of CRC xenografts generated from isolated quasi-mesenchymal cells (M phenotype) with enhanced tumourigenic properties. These cells have enhanced tumourigenic properties.
Smiles
Cc1cc(Nc2ccc(NC(=O)Cc3cc(Br)cs3)cc2)nc(n1)N1CCCC1
Molecular Formula
C21H22BrN5OS
Molecular Weight
472.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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