Recombinant Rat Interleukin-7 (Il7)

CAT: 0399-CSB-EP011669RA-01Size: 20 µgDry Ice: NoHazardous: No

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CAT#:0399-CSB-EP011669RA-01Size:20 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Abbreviation

Recombinant Rat Il7 protein

Gene Name

Il7

UniProt

P56478

Expression Region

26-154aa

Organism

Rattus norvegicus (Rat)

Target Sequence

DCHIKDKDGKAFGSVLMISINQLDKMTGTDSDCPNNEPNFFKKHLCDDTKEAAFLNRAARKLRQFLKMNISEEFNDHLLRVSDGTQTLVNCTSKEEKTIKEQKKNDPCFLKRLLREIKTCWNKILKGSI

Tag

C-terminal 6xHis-tagged

Type

Developed Protein

Source

E.coli

Field of Research

Immunology

Relevance

Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5

Purity

Greater than 85% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.208.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Molecular Weight

21.8 kDa

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Protein Length

Full Length of Mature Protein

UniProtKB · P56478

Interleukin-7

IL7_RAT · Rattus norvegicus

View on UniProt ↗

Primary accession: P56478
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Il7
Protein existence: 2: Evidence at transcript level
Organism: Rattus norvegicus (Rat)
Taxonomy ID: 10116
Alternative names: IL-7
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoprotein

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

Related Products

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CSB-EP011669BO-01	Recombinant Bovine Interleukin-7 (IL7)
CSB-CF011669HU-01	Recombinant Human Interleukin-7 (IL7)
CSB-AP004491HU-01	Recombinant Human Interleukin-7 (IL7) (Active)
CSB-MP011669HU-WD-01	Recombinant Human Interleukin-7 (IL7) (Active)
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CSB-AP003331MO-01	Recombinant Mouse Interleukin-7 protein (Il7) (Active)
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Alternative Products

Catalog	Name
MBS2030647-01	Recombinant Interleukin 7 (IL7)
MBS961732-01	Recombinant Mouse Interleukin-7 (Il7)
RPC28646-01	Recombinant Bovine Interleukin-7 (IL7)
RPU54326-01	Recombinant Rabbit Interleukin 7 (IL7)
155453-01	Interleukin 7 (IL7) Recombinant, Mouse
MBS717711-01	Recombinant Rat Interleukin-7 (Il7)
MBS1410540-01	Recombinant Sheep Interleukin-7 (IL7)
GTR19134175-01	Recombinant Human Interleukin-7 (IL7)
223606-01	IL7 (IL 7, IL-7, Il7, IL7, Interleukin 7, Interleukin-7) discontinued
483518	IL7 (Interleukin-7)