CD73-IN-5

• UNSPSC Description:

  CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (IC50 = 19 nM).

• Target Antigen:

  CD73

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cd73-in-5.html

• Solubility:

  DMSO : ≥ 50 mg/mL

• Smiles:

  N#CC1=CC=C(CN2N=CC=C2C3=CC4=C(N=NN4C5=CC6=C(C=NN6)C=C5)C(F)=C3)C=C1

• Molecular Weight:

  434.43

• References & Citations:

  [1]Beatty JW, et al. Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J Med Chem. 2020 Apr 23;63(8):3935-3955.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2412019-99-7