Products for Research Use Only

Recombinant Rat M-CSF - 2 μg

CAT: 1161-M1227-2μgSize: 2 µgDry Ice: NoHazardous: No
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CAT#:1161-M1227-2μgSize:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Colony-Stimulating Factor 1 (CSF-1), also known as Macrophage Colony-Stimulating Factor (M-CSF), is the primary inducer for cells of the monocyte/macrophage lineage. Macrophages are critical innate immune cells, making CSF-1 central to immunological defenses and the body's response to infection and disease. Beyond immunity, CSF-1 plays diverse and crucial biological roles, including: - Bone Metabolism: CSF-1 is necessary for the differentiation and survival of osteoclasts, the cells responsible for bone resorption. - Lipoprotein Clearance: It helps regulate lipid processing and the clearance of lipoproteins from the bloodstream. - Reproduction: CSF-1 is vital for fertility and pregnancy, supporting successful embryonic development and placental function. This wide range of functions positions CSFs, particularly CSF-1, as key regulatory factors in immunology, endocrinology, and bone health, making them important targets for research.
Target
M-CSF
Field of Research
Other Molecules
Shipping Conditions
Next Day Ambient
Storage Conditions
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation
The recombinant M-CSF protein was subjected to extensive dialysis using PBS before being lyophilized (freeze-dried) to yield the final product.