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M-CSF Recombinant Protein

CAT: 0223-40-606Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-606Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant human M-CSF is a 36.8 kDa homodimeric protein containing two 159 amino acid polypeptide subunits.
CAS Number
9000-83-3
NCBI Gene ID
1435
Swiss Prot
P09603
Accession Number
NP_000748.3
Type
Recombinant Proteins
Source
E. coli
Field of Research
Growth Factors, Immunology, Signal Transduction
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized M-CSF recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted M-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing M-CSF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Colony stimulating factor 1 (macrophage)
NCBI Organism
Homo sapiens
Other Product Names
MCSF, CSF-1, Macrophage colony-stimulating factor 1, Lanimostim
Species
Human
Protein ID
27262661
Physical Properties
Lyophilized

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