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E-3030 (free acid)

CAT: 0804-HY-117459Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117459Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E-3030 free acid is a potent dual activator of peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma, exhibiting significant antidiabetic and lipid-modulating effects. E-3030 decreases blood glucose, triglyceride, non-esterified fatty acids, and insulin levels, while increasing blood adiponectin levels. E-3030 improves glucose tolerance and shows remarkable triglyceride- and non-high-density lipoprotein cholesterol-lowering effects in animal models.
CAS Number
478926-45-3
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/e-3030-free-acid.html
Smiles
O=C(O)[C@@H](OC(C)C)CC1=CC=CC(OC[C@H](F)COC2=CC=C(Cl)C=C2C#N)=C1
Molecular Formula
C22H23ClFNO5
Molecular Weight
435.87
References & Citations
[1]Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, E3030, in db/db mice and beagle dogs
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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