Hsp70-derived octapeptide

• UNSPSC Description:

  Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs[1][2].

• Target Antigen:

  HSP

• Type:

  Peptides

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Neurological Disease; Infection

• Assay Protocol:

  https://www.medchemexpress.com/hsp70-derived-octapeptide.html

• Purity:

  98.01

• Solubility:

  H2O : 1.82 mg/mL (ultrasonic;adjust pH to 1 with HCl)

• Smiles:

  O=C(O)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H]([C@H](O)C)NC([C@H]1N(C(CN)=O)CCC1)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  858.89

• References & Citations:

  [1]Tutar Y, et al. Primate chaperones Hsc70 (constitutive) and Hsp70 (induced) differ functionally in supportinggrowth and prion propagation in Saccharomyces cerevisiae. Genetics. 2006 Feb;172(2):851-61.|[2]Kajander T, et al. Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. J Biol Chem. 2009 Sep 11;284(37):25364-74.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  736171-62-3