Deruxtecan analog 2

• Description:

  Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC[1].

• UNSPSC:

  12352203

• Target:

  Drug-Linker Conjugates for ADC

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/deruxtecan-analog-2.html

• Purity:

  99.56

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (N[C@H]1CCC2=C3C1=C (CN4C (C (COC ([C@@]5 (CC) O) =O) =C5C=C46) =O) C6=NC3=CC (F) =C2C) COCNC (CN) =O

• Molecular Formula:

  C29H30FN5O7

• Molecular Weight:

  579.58

• References & Citations:

  [1]Daly Christopher, et, al. Anti-FGFR2 antibodies and antibody-drug conjugates methods of use thereof. Patent WO2022087243.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• CAS Number:

  1599440-10-4