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S 38093

CAT: 0804-HY-104003-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-104003-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S 38093 is a brain-penetrant, orally active antagonist of H3 receptor, with Kis of 8.8, 1.44 and 1.2 μM for rat, mouse and human H3 receptors, respectively.
CAS Number
862896-30-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/S_38093.html
Purity
99.86
Solubility
DMSO : 2 mg/mL (ultrasonic)
Smiles
O=C(N)C1=CC=C(OCCCN2CC3C(CCC3)C2)C=C1
Molecular Formula
C17H24N2O2
Molecular Weight
288.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Guilloux JP, et al. S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice. Sci Rep. 2017 Feb 20;7:42946.|[2]Sors A, et al. Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptors. Eur J Pharmacol. 2017 May 15;803:11-23
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor

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