Forsythoside I

CAT: 0804-HY-N5042-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N5042-01Size:5 mg
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Description
Forsythoside I is an orally active caffeoyl phenylethanoid glycoside (CPG) that can be isolated from Forsythia suspense (Thunb.) Vahl. Forsythoside I has anti-inflammatory activity and can exert a protective effect in a mouse model of acute lung injury[1][2].
CAS Number
[1177581-50-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Arrestin; Caspase; Interleukin Related; NOD-like Receptor (NLR) ; SOD
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/forsythoside-i.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]([C@@H](OC(/C=C/C1=CC=C(O)C(O)=C1)=O)[C@@H]([C@@H](CO[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)O)O3)O)[C@@H]3OCCC4=CC=C(O)C(O)=C4
Molecular Formula
C29H36O15
Molecular Weight
624.59
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang FN, et al. New phenylethanoid glycosides from the fruits of forsythia suspense (thunb.) vahl. Molecules. 2009 Mar 25;14 (3) :1324-31.|[2]Liang H, et al. Potential of Forsythoside I as a therapeutic approach for acute lung injury: Involvement of TXNIP/NLRP3 inflammasome. Mol Immunol. 2021 Jun;134:192-201.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 1; IL-1; IL-6; NLRP3

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