Alphitolic acid

CAT: 0804-HY-N2855-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-N2855-01Size:500 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Alphitolic acid (Aophitolic acid) is an anti-inflammatory triterpene could found in quercus aliena. Alphitolic acid blocks Akt–NF-κB signaling to induce apoptosis. Alphitolic acid induces autophagy. Alphitolic acid has anti-inflammatory activity and down-regulates the NO and TNF-α production. Alphitolic acid can be used for cancer and inflammation research[1][2][3].
CAS Number
[19533-92-7]
Product Name Alternative
Aophitolic acid
UNSPSC
12352211
Target
Akt; Apoptosis; Autophagy; NF-κB; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alphitolic-acid.html
Purity
97.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H]([C@@H](C5)O)O)C)([H])CC4)C)([H])CC3)C)C)=O
Molecular Formula
C30H48O4
Molecular Weight
472.70
References & Citations
[1]Bai LY, et, al. Alphitolic acid, an anti-inflammatory triterpene, induces apoptosis and autophagy in oral squamous cell carcinoma cells, in part, through a p53-dependent pathway. 2015 Jan 22; 18 (2015) :368-378.|[2]Raju R, et, al. Anti-Inflammatory Chemical Profiling of the Australian Rainforest Tree Alphitonia petriei (Rhamnaceae) . Molecules. 2016 Nov 11;21 (11) :1521. |[3]Goity LE, et, al. An HPLC-UV and HPLC-ESI-MS based method for identification of antiinflammatory triterpenoids from the extracts of Ugni molinae. 2013 Jan; 12 (1) :108-116.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N8341-01Alphitonin
HY-140589Acid-PEG4-S-PEG4-acid
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-N9688Jacoumaric acid
HY-D2445-01AF405 acid
HY-125715-01Trigalacturonic acid
HY-125909Phenolic acid

Alternative Products

CatalogName
BUP23111Alphitolic acid
OR1071368-01Acid-apeg6-acid
MBS6083807-01Medronic Acid (Methylenebiphosphonic Acid, Methylenediphosphonic Acid, Methanebisphosphonic Acid, Methanediphosphonic Acid, MDP)
041005Cacodylic Acid (dimethylarsonic acid, dimethylarsinic acid)
L2500-01Lipoic Acid (Thioctic Acid, (±) -α-Lipoic Acid)
MBS641082-01Lipoic Acid (Thioctic Acid, Alpha Lipoic Acid)
MBS6036559-01a-Lipoic Acid (Thioctic Acid)
MBS651473-01Ambuic acid ((+)-Ambuic acid)
64200302-500gOctanoic acid (Caprylic acid)
18131235Mercaptosuccinic acid (Thiomalic acid)

Popular Products