KLK2 Polyclonal Antibody

CAT: 0763-D-AB-10371L-01Size: 25 µLDry Ice: NoHazardous: No

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CAT#:0763-D-AB-10371L-01Size:25 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Abbreviation

KLK2

UniProt

P20151

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human KLK2 protein expressed by E.coli

Target

Glandular kallikrein 2; Glandular kallikrein-1; hGK 1; hGK-1; hK2; Kallikrein 2 prostatic; Kallikrein related peptidase 2; kallikrein; glandular; Kallikrein; prostatic; Kallikrein-2; KLK 2; Klk-2; Klk2; KLK2; KLK2A 2; KLK2A2; MGC12201; Tissue kallikrein 2; Tissue kallikrein-2; Ton

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology; Signal Transduction

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

IHC 1:1000-1:2000

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

UniProtKB · P20151

Kallikrein-2

KLK2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P20151
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: KLK2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.35
Processing: Precursor
Secondary accessions: B4DU93, B4DUB0, F5H8L3, Q15946, Q9UJZ9

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinZymogen

Molecular function

HydrolaseProteaseSerine protease

Domain

Signal

Product Datasheet

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