KLK6 Polyclonal Antibody

• Background :

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

• Abbreviation :

  KLK6

• UniProt :

  Q92876

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human KLK6

• Target :

  Bssp; hK 6; hK6; Kallikrein 6 precursor; Kallikrein related peptidase 6; Kallikrein-6; Kallikrein6; KLK 6; Klk 7; KLK 9; Klk29; Klk6; KLK6; Klk7; KLK9; MGC9355; mGK 1; mGK1; MSP; Neurosin; Protease M; Protease serine 18; Protease serine 9; PRSS 18; PRSS 9; PRSS18; PRSS9; Serine protease 18; Serine protease 9; SP 59; SP59; Tissue kallikrein; TK; Zyme

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Cancer; Cell Biology; Neuroscience; Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.4 mg/mL

• Dilution :

  IHC 1:100-1:300

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG