DJ-53

• Description:

  DJ-53 (compund 68) is an orally active phenylquinoline-based soluble epoxide hydrolase inhibitor[1].

• UNSPSC:

  12352005

• Target:

  Epoxide Hydrolase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dj-53.html

• Smiles:

  COC1=CC(C2=CC3=CC=C(C=C3N=C2)NC(NCC4=CC=C(C=C4)OC(F)(F)F)=O)=CC(OC)=C1

• Molecular Formula:

  C26H22F3N3O4

• Molecular Weight:

  497.47

• References & Citations:

  [1]Ding J, et al. Discovery of Orally Active Phenylquinoline-Based Soluble Epoxide Hydrolase Inhibitors with Anti-Inflammatory and Analgesic Activity. J Med Chem. 2024 Oct 24;67 (20) :18412-18447.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported