6-Hydroxywarfarin

• Description:

  6-Hydroxywarfarin is a metabolite of (+) -warfarin. 6-Hydroxywarfarin is a weaker vitamin K antagonist. 6-Hydroxywarfarin is metabolized by the cytochrome P450 isomer 2C9 (CYP2C9) [1].

• Product Name Alternative:

  (S)​-​(+)​-​Abscisic acid; ABA

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Cytochrome P450

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/6-hydroxywarfarin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1OC2=CC=C(C=C2C(O)=C1C(CC(C)=O)C3=CC=CC=C3)O

• Molecular Formula:

  C19H16O5

• Molecular Weight:

  324.33

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Hartman G, et al. The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening. Bioorg Med Chem Lett. 2024 Feb 28;102:129675.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [17834-02-5]