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L 657925

CAT: 0804-HY-121720Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121720Size:1 Each
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Description
L 657925 is a potent thromboxane A2 (TXA2) antagonist. L 657925 selectively abolishes ONO 11113-evoked transient increment in [Ca22+][1].
CAS Number
122757-59-9
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-657925.html
Smiles
FC1=CC=C(N(C2([H])C3([H])CCCC2CC(O)=O)CC4=CC=C(C=C4)Cl)C3=C1
Molecular Formula
C21H21ClFNO2
Molecular Weight
373.85
References & Citations
[1]Ueda N, et al. Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2. Kidney Int. 1991 Dec;40 (6) :1075-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TXA2/TP

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