CDK7-IN-1

CDK7-IN-1

• CAS Number: 1957203-02-9
• UNSPSC Description: CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/YKL-5-124_Analogs.html
• Purity: 98.91
• Solubility: 10 mM in DMSO
• Smiles: CC1(C)N(C(N[C@@H](C2=CC=CC=C2)CN(C)C)=O)CC3=C1NN=C3NC(C4=CC=C(NC(CC)=O)C=C4)=O
• Molecular Weight: 517.62
• References & Citations: [1]Nathanael S. Gray, et al Inhibitors of cyclin-dependent kinase 7 (cdk7). WO 2016105528 A2
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported