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CDK7-IN-1

CAT: 0804-HY-101257ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101257ASize:1 Each
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Description
CDK7-IN-1, an analog of YKL-5-124, is a cyclin-dependent kinase 7 (cdk7) inhibitor, with an IC50 of less than 100 nM, extracted from patent WO 2016105528 A2, Compound 215[1].
CAS Number
1957203-02-9
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/YKL-5-124_Analogs.html
Purity
98.91
Solubility
10 mM in DMSO
Smiles
CC1(C)N(C(N[C@@H](C2=CC=CC=C2)CN(C)C)=O)CC3=C1NN=C3NC(C4=CC=C(NC(CC)=O)C=C4)=O
Molecular Formula
C28H35N7O3
Molecular Weight
517.62
References & Citations
[1]Nathanael S. Gray, et al Inhibitors of cyclin-dependent kinase 7 (cdk7) . WO 2016105528 A2
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7

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