Thalidomide-O-amido-C8-NH2 (hydrochloride)

CAT:

804-HY-107439A-03

Size:

25 mg

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CAS Number: 2415263-07-7
UNSPSC Description: Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/thalidomide-o-amido-c8-nh2-hydrochloride.html
Solubility: 10 mM in DMSO
Smiles: O=C(NCCCCCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.Cl
Molecular Weight: 494.97
References & Citations: [1]James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-107439A-03	Thalidomide-O-amido-C8-NH2 (hydrochloride)
HY-107439A-02	Thalidomide-O-amido-C8-NH2 (hydrochloride)
HY-107439A-01	Thalidomide-O-amido-C8-NH2 (hydrochloride)
HY-107439	Thalidomide-O-amido-C8-NH2
HY-103614-01	Thalidomide-O-amido-C8-NH2 (TFA)
HY-138853A	Thalidomide-NH-amido-C8-NH2 (hydrochloride)
HY-103614-03	Thalidomide-O-amido-C8-NH2 (TFA)
HY-103614-02	Thalidomide-O-amido-C8-NH2 (TFA)
HY-138853	Thalidomide-NH-amido-C8-NH2
HY-149565-01	Thalidomide-5-O-C8-NH2 (hydrochloride)

Cat	Name
T18817-5mg	Thalidomide-O-amido-C8-NH2 hydrochloride
T18817-10mg	Thalidomide-O-amido-C8-NH2 hydrochloride
T18817-1g	Thalidomide-O-amido-C8-NH2 hydrochloride
T18817-1mg	Thalidomide-O-amido-C8-NH2 hydrochloride
T18817-50mg	Thalidomide-O-amido-C8-NH2 hydrochloride
T17819-1mg	Thalidomide-O-amido-C8-NH2
MBS3844623-03	Thalidomide-O-amido-C8-NH2
T17819-1g	Thalidomide-O-amido-C8-NH2
T17819-50mg	Thalidomide-O-amido-C8-NH2
T17819-10mg	Thalidomide-O-amido-C8-NH2