2,5-Dihydroxyacetophenone

• Description:

  2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ERK; NF-κB

• Type:

  Natural Products

• Related Pathways:

  MAPK/ERK Pathway; NF-κB; Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html

• Concentration:

  10mM

• Purity:

  99.95

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C1=CC(O)=CC=C1O)=O

• Molecular Formula:

  C8H8O3

• Molecular Weight:

  152.15

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  Rehmanniae Radix

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  ERK1; ERK2; NF-κB

• CAS Number:

  [490-78-8]