2,5-Dihydroxyacetophenone

• Description :

  2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ERK; NF-κB

• Type :

  Natural Products

• Related Pathways :

  MAPK/ERK Pathway; NF-κB; Stem Cell/Wnt

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html

• Concentration :

  10mM

• Purity :

  99.95

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC(C1=CC(O)=CC=C1O)=O

• Molecular Formula :

  C8H8O3

• Molecular Weight :

  152.15

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  Rehmanniae Radix

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  ERK1; ERK2; NF-κB

• CAS Number :

  [490-78-8]