Oxybenzone

CAT: 0804-HY-A0067-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-A0067-01Size:500 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[1][2][3].
CAS Number
[131-57-7]
Product Name Alternative
Benzophenone 3
UNSPSC
12352005
Hazard Statement
H400, H411
Target
Apoptosis; Autophagy; RAR/RXR
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Oxybenzone.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(C1=CC=C(OC)C=C1O)C2=CC=CC=C2
Molecular Formula
C14H12O3
Molecular Weight
228.25
Precautions
H400, H411
References & Citations
[2]DiNardo JC, et al. Can oxybenzone cause Hirschsprung's disease?. Reprod Toxicol. 2019;86:98-100.|[3]Wnuk A, et al. Benzophenone-3 Impairs Autophagy, Alters Epigenetic Status, and Disrupts Retinoid X Receptor Signaling in Apoptotic Neuronal Cells. Mol Neurobiol. 2018;55 (6) :5059-5074.|[4]Wnuk A, et al. Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons. J Steroid Biochem Mol Biol. 2018;182:106-118.|[1]Wnuk A, et al. Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons. J Steroid Biochem Mol Biol. 2018;182:106-118.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
MBS3841429-01Oxybenzone
TRC-O867302-25MGOxybenzone-d3
MF-0117905-01Oxybenzone-13C6
A16141-1000Oxybenzone 1000mg
A16141-5000Oxybenzone 5g
A16141-500Oxybenzone 500mg

Popular Products