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Oxybenzone-13C6

CAT: 0804-HY-A0067S1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-A0067S1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxybenzone-13C6 (Benzophenone 3-13C6) is the 13C-labeled Oxybenzone (HY-A0067) . Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells[1][2][3].
Product Name Alternative
Benzophenone 3-13C6
UNSPSC
12352005
Target
Apoptosis; Autophagy; Isotope-Labeled Compounds; RAR/RXR
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C1=CC=C(OC)C=C1O)[13C]2=[13CH][13CH]=[13CH][13CH]=[13CH]2
Molecular Formula
C8 13C6H12O3
Molecular Weight
234.20
References & Citations
[1]Wnuk A, et al. Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons. J Steroid Biochem Mol Biol. 2018;182:106-118. |[2]DiNardo JC, et al. Can oxybenzone cause Hirschsprung's disease?. Reprod Toxicol. 2019;86:98-100.|[3]Wnuk A, et al. Benzophenone-3 Impairs Autophagy, Alters Epigenetic Status, and Disrupts Retinoid X Receptor Signaling in Apoptotic Neuronal Cells. Mol Neurobiol. 2018;55 (6) :5059-5074.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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