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Recombinant Human CNTF Protein

CAT: 0793-32-18095-50Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0793-32-18095-50Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Molecular weight: 22.93 KDaDescription: Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli and the target gene encoding Ala2-Met200 is expressed.Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
Product Name Alternative
Ciliary Neurotrophic Factor; CNTF
UniProt
P26441
Host
E.coli
Target Antigen
CNTF
Components
Lyophilized from a 0.2 ?m filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.

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