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CNTF Protein, Human, Recombinant

CAT: 0931-TMPJ-00081-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0931-TMPJ-00081-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Purity
0.95
Bioactivity
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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