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Polyclonal Antibody to DP-1

CAT: 0793-35-1822-100Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0793-35-1822-100Size:100 µL
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Description
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis. Wu C.-L., Zukerberg L.R., Ngwu C., Harlow E., Lees J.A.Mol. Cell. Biol. 15:2536-2546 (1995)
Product Name Alternative
Dp-1|| TFDP1|| DRTF1
Gene Name
TFDP1
Gene ID
7027
UniProt
Q14186
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Peptide sequence around aa.13~17 (E-L-K-V-F) derived from Human DP-1
Target Antigen
DP-1
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 45kd, Western blotting: 1:500~1:1000
Isotype
Rabbit IgG

UniProtKB · Q14186

Transcription factor Dp-1

TFDP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14186
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TFDP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DLQ9, Q5JSB4, Q8IZL5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleTranscriptionTranscription regulation

Cellular component

CytoplasmNucleus

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