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Anti-Human CD253 APC (Clone : 2E5)

CAT: 0793-30-2613-0.1Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0793-30-2613-0.1Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2) .Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
Product Name Alternative
TRAIL, Apo-2 ligand, Apo-2L, TNFSF10, APO2L, TNLG6A, TNF superfamily member 10
Gene Name
TNFSF10
Gene ID
8743
Reactivity
Human
Immunogen
Recombinant soluble fragment (aa 95-281) of human TRAIL.
Target Antigen
CD253
Clonality
Monoclonal
Clone
2E5
Applications
FACS
Purification
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Components
0.1 mg/mLFormulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Mouse IgG1
Conjugate
APC

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