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Polyclonal Antibody to Hes7

CAT: 0793-11-8084-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0793-11-8084-100Size:100 µg
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Description
HES7 (Hes family bHLH transcription factor 7) is a member of the Hairy-and-enhancer-of-split (HES) family of transcription factors, which play a role in somite formation. This is expressed in an oscillatory manner during the process of somitogenesis, a process by which somites (bilaterally paired blocks of mesoderm) form and give rise to skeletal muscle, cartilage, tendons, endothelial cells, and dermis. Missense mutations of HES7 have been reported to cause SCDO4 (Spondylocostal Dysostosis 4), an inherited disorder that is characterized by the presence of extensive hemivertebrae, truncal shortening and abnormally aligned ribs.
Product Name Alternative
HES7||BHLHB37
Gene Name
HES7
Gene ID
84667
UniProt
Q9BYE0
Host
Rabbit
Reactivity
Human
Immunogen
Full length recombinant Hes7 protein was used as the immunogen for this antibody.
Target Antigen
Hes7
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 0.5-1μg/mL
Isotype
Rabbit IgG

UniProtKB · Q9BYE0

Transcription factor HES-7

HES7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BYE0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HES7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hHes7
EC number
—
Processing
—
Secondary accessions
F8VPC9
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Developmental proteinDNA-bindingRepressor

Disease

Disease variantDwarfism

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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GTR18203583HES7 Polyclonal Antibody
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