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Polyclonal Antibody to Cox2

CAT: 0793-35-1847-50Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0793-35-1847-50Size:50 μL
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Description
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Product Name Alternative
COX-2||PHS-2||PGG/HS||PGHS-2||hCox-2
Gene Name
PTGS2
Gene ID
5743
UniProt
P35354
Host
Rabbit
Reactivity
Human
Immunogen
Peptide sequence around aa.596-600 (L-L-K-E-R) derived from Human Cox2.
Target Antigen
Cox2
Clonality
Polyclonal
Applications
WB
Format
Purified
Components
1.0 mg/mL,100 μl
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Predicted MW: 74kd, Western blotting: 1: 500~1: 1000
Isotype
Rabbit IgG

UniProtKB · P35354

Prostaglandin G/H synthase 2

PGH2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35354
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PTGS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.99.1
Processing
Precursor
Secondary accessions
A8K802, Q16876
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinS-nitrosylation

Molecular function

DioxygenaseOxidoreductasePeroxidase

Cellular component

Endoplasmic reticulumMembraneMicrosomeNucleus

Biological process

Fatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolismProstaglandin biosynthesisProstaglandin metabolism

Ligand

HemeIronMetal-binding

Domain

Signal

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