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Polyclonal Antibody to ASAP2

CAT: 0793-11-8068-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0793-11-8068-25Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ASAP2 (Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2) or Development and differentiation-enhancing factor 2 (DDEF2) or Paxillin-associated protein with ARF GAP activity 3 (PAG3) is a multidomain protein containing two ANK repeats, one Arf-GAP domain, one PH domain and one SH3 domain. ASAP2 has two isoforms: PAPalpha and PAPbeta (111 and 106 kDa respectively) and both the isoforms are generally located in Golgi plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2) . ASAP2 regulates ARF-mediated vesicle budding when vesicular transport. ASAP2 has high level of expression in brain, kidney, and heart.
Product Name Alternative
ASAP2||DDEF2||KIAA0400
Gene Name
ASAP2
Gene ID
8853
UniProt
O43150
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant ASAP2 protein (amino acids 500-760) was used as the immunogen for this antibody.
Target Antigen
ASAP2
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4μg/mL
Isotype
Rabbit IgG

UniProtKB · O43150

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

ASAP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43150
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ASAP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D6W4Y8
Protein keywords

Coding sequence diversity

Alternative splicing

Domain

ANK repeatCoiled coilRepeatSH3 domain

Cellular component

Cell membraneCytoplasmGolgi apparatusMembrane

Molecular function

GTPase activation

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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