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Polyclonal Antibody to ASAP3

CAT: 0793-11-8066-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0793-11-8066-25Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ASAP3 belongs to Arf-specific GTPase-activating proteins which regulate Arfs by stimulating their intrinsic GTP hydrolysis. This protein contains a catalytic core of a PH (Pleckstrin Homology) domain, a GAP motif, and two ANK (Ankyrin) repeats. ASAP3 also associates with focal adhesions and with cytoplasmic membranes at the circular dorsal ruffles, where the actin skeleton is remodeled. Depletion of ASAP3 by RNA interference suppresses cell migration in wound healing.
Product Name Alternative
ASAP3||DDEFL1||UPLC1
Gene Name
ASAP3
Gene ID
55616
UniProt
Q8TDY4
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant ASAP3 protein (amino acids 550-800) was used as the immunogen for this antibody.
Target Antigen
ASAP3
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL This antibody detects ~43 kDa band. The size corresponds to Isoform 2 (Uniprot ID-Q8TDY4-2) of ASAP3, the right size is ~99 kDa.
Isotype
Rabbit IgG

UniProtKB · Q8TDY4

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3

ASAP3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TDY4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ASAP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B3KRW0, B4DHH4, Q6P9F4, Q86UY1, Q9NXK2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

ANK repeatCoiled coilRepeatZinc-finger

Cellular component

Cytoplasm

Ligand

Metal-bindingZinc

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