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Polyclonal Antibody to ST2

CAT: 0793-11-3002-25Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0793-11-3002-25Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ST2V or ST2 is a member of the interleukin 1 receptor family. It acts as receptor for interleukin-33 (IL33) and its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6, followed by phosphorylation of MAPK3/ERK1. Diseases associated with ST2V are yellow fever and allergic conjunctivitis. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine and has four isoforms produced by alternate splicing.
Product Name Alternative
IL1RL1||DER4||ST2||T1
Gene Name
IL1RL1
Gene ID
9173
UniProt
Q01638
Host
Rabbit
Reactivity
Human
Immunogen
A partial length recombinant ST2V protein (amino acids 150-300) was used as the immunogen for this antibody.
Target Antigen
ST2V or ST2
Clonality
Polyclonal
Applications
WB
Purification
Protein A Chromatography
Format
Purified
Components
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Western blot analysis: 2-4 μg/mL This antibody detects ~34 kDa band. The size corresponds to Isoform 2 (Uniprot ID-Q01638-2) of ST2, the right size is ~63 kDa.
Isotype
Rabbit IgG

UniProtKB · Q01638

Interleukin-1 receptor-like 1

ILRL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01638
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL1RL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.2.2.6
Processing
Precursor
Secondary accessions
A8K6B3, B4E0I3, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinIsopeptide bondUbl conjugation

Molecular function

HydrolaseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Ligand

NAD

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