IL17A Protein (Native, Human)

CAT: 1543-P521224Size: 100 µgDry Ice: NoHazardous: No
CAT#:1543-P521224Size:100 µg
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Abbreviation
IL17A
Synonyms
CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17
Host
E. coli
Tag
Native
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
≥ 95 % as determined by SDS-PAGE
Bioactivity
1.Measured by its ability to induce IL-6 secretion by NIH‐3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.5-2.5 ng/mL. 2.Recombinant Human IL-17RA Protein, hFc Tag (Cat. No. 10895-H02H) captured on Protein A chip can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 0.190 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) . 3.Anti-IL17A (Research Grade Ixekiz*mab Biosimilar) captured on Protein A chip, can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 24.450 pM pM as determined in an SPR assay (Biacore T200) (Routinely tested) . 4.Anti-IL17A (Research Grade Secukin*mab Biosimilar) captured on Protein A chip, can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 65.890 pM as determined in an SPR assay (Biacore T200) (Routinely tested) .
Function
Ile20-Ala155
Molecular Weight
The recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa.
Species
Human

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