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Human IL17A & IL17F protein

CAT: 0013-GTR18885473-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18885473-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human IL17A & IL17F protein spans the amino acid sequence from region 24-155aa & 31-163aa. Purity: Greater than 95% as determined by SDS-PAGE.
Product Name Alternative
IL‐17A/F Heterodimer; IL-17A&IL-17F Heterodimer
UniProt
Q16552
Expression Region
24-155aa&31-163aa
Tag
C-terminal 6xHis-tagged
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
Greater than 95% as determined by SDS-PAGE.
Bioactivity
1Loaded Biotinylated Human IL-17RA -His-Avi on SA Biosensor, can bind Human IL-17A&17F-His with an affinity constant of 8.6 pM as determined in BLI assay. 2Loaded Biotinylated Human IL-17RA-Fc on Pro A Biosensor, can bind Human IL-17A&17F-His with an affinity constant of 10.3 nM as determined in BLI assay.
Form
Lyophilized powder
Molecular Weight
15.1kDa & 16.0 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Heterodimer
Preservative
Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4
AA Sequence
GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA &RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHRVQ

UniProtKB · Q16552

Interleukin-17A

IL17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16552
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL17A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-17, IL-17A
EC number
—
Processing
Precursor
Secondary accessions
Q5T2P0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityImmunityInflammatory responseInnate immunity

Molecular function

Cytokine

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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