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IL-1 Protein (Human)

CAT: 1543-P515920Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P515920Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Abbreviation
IL-1
Synonyms
IL1F, IL-1F, pro IL1F, IL-1, IL1-BETA, IL1F2, IL1 beta, IL1B, catabolin, IL-1B, pro Catabolin, pro IL1B, pro IL1F2, pro leukocytic endogenous mediator, pro leukocytic pyrogen, pro lymphocyte activating factor, pro mononuclear cell factor, IL-1F2, IL 1B, IL-1 beta
UniProt
P01584
Host
E. coli
Applications
Cell culture, ELISA
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
1. Immobilized recombinant human IL1B at 2 μg/mL (100μl/well) can bind recombinant human IL1R2 with a linear range of 6. 25-400 ng/ml. 2. Measured in a cell proliferation assay using D10.G4. 1 mouse helper T cells. The ED50 for this effect is typically 2-8 pg/mL. 3. Immobilized human IL1B at 10 μg/mL (100 μl/well) can bind human IL1R1, The EC50 of human IL1R1 is 0.48 μg/mL. 4. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.4-2 ng/mL.
Function
Ala 117-Ser 269
Molecular Weight
17 kDa
Species
Human

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