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TIMP2/TIMP-2 Protein (Human)

CAT: 1543-P518810Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P518810Size:100 µg
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Abbreviation
TIMP2/TIMP-2
Synonyms
CSC-21K, DDC8, Metalloproteinase Inhibitor 2, Tissue Inhibitor of Metalloproteinases 2
UniProt
P16035
Host
HEK 293
Applications
Enzyme
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 96 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 4 nM.
Function
Cys 27-Pro 220
Molecular Weight
22 kDa
Species
Human

UniProtKB · P16035

Metalloproteinase inhibitor 2

TIMP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P16035
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TIMP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q16121, Q93006, Q9UDF7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Disulfide bond

Ligand

Metal-bindingZinc

Molecular function

Metalloenzyme inhibitorMetalloprotease inhibitorProtease inhibitor

Cellular component

Secreted

Domain

Signal

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Alternative Products

CatalogName
E53A06901Recombinant Human TIMP2 / TIMP-2 Protein
PKSH031634Recombinant Human TIMP2/TIMP-2 Protein
600-261-L20Human TIMP2 / TIMP-2 Protein (hFc Tag)
PKSH033118-01Recombinant Human TIMP2/TIMP-2 Protein (His Tag)
E53A06670Recombinant Human TIMP2 / TIMP-2 Protein (Fc tag)
PKSH030472Recombinant Human TIMP2/TIMP-2 Protein (Fc Tag)
QP10162-ec-100ugRecombinant Human TIMP2/ TIMP-2 Protein, Untagged, E.coli-100ug
QP8571-ec-500ugRecombinant Human TIMP2/ TIMP-2 Protein, GST, E.coli-500ug
QP10162-ec-250ugRecombinant Human TIMP2/ TIMP-2 Protein, Untagged, E.coli-250ug
QP10162-ec-2ugRecombinant Human TIMP2/ TIMP-2 Protein, Untagged, E.coli-2ug

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