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Notch2 Protein (C-His, Human)

CAT: 1543-P517263Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P517263Size:100 µg
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Abbreviation
Notch2
Synonyms
AGS2, HJCYS, Notch homolog 2, Notch-2, Notch2, hN2
UniProt
Q04721
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Function
Leu26-Gln530
Molecular Weight
54.9 kDa
Species
Human

UniProtKB · Q04721

Neurogenic locus notch homolog protein 2

NOTC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q04721
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 2, hN2
EC number
—
Processing
Precursor
Secondary accessions
Q5T3X7, Q99734, Q9H240
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Cell membraneCytoplasmMembraneNucleus

Biological process

DifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Disease

Disease variantOsteoporosis

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation