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Protein (C-His, Human)

CAT: 1543-P513110Size: 100 µgDry Ice: NoHazardous: No
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CAT#:1543-P513110Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Synonyms
CD32, CDw32, FCG2, FCGR2B, Fc-Gamma RII-b, Fc-Gamma-RIIb, FcRII-b, IGFR2, IgG Fc Receptor II-b, Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b
UniProt
P31994
Host
CHO Cells
Tag
C-His
Applications
ELISA
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 97 % as determined by reducing SDS-PAGE.
Bioactivity
Immobilized human sCD32b-His (CHO) at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.18-0.42 μg/ml.
Function
Ala46-Pro217
Molecular Weight
20.8 kDa
Species
Human

UniProtKB · P31994

Low affinity immunoglobulin gamma Fc region receptor II-b

FCG2B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31994
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FCGR2B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IgG Fc receptor II-b
EC number
—
Processing
Precursor
Secondary accessions
A6H8N3, O95649, Q53X85, Q5VXA9, Q8NIA1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

Host-virus interaction

Molecular function

IgG-binding proteinReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Disease

Proto-oncogeneSystemic lupus erythematosus