Ac-WEHD-AFC (TFA)

Ac-WEHD-AFC (TFA)

• UNSPSC Description: Ac-WEHD-AFC TFA is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation[1].
• Target Antigen: Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/ac-wehd-afc-tfa.html
• Purity: 99.01
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
• Smiles: FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC5=CN=CN5)=O)=O)=CC1=O)F.OC(C(F)(F)F)=O
• Molecular Weight: 952.77
• References & Citations: [1]Katherine Labbé, et al. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity. 2011 Dec 23;35(6):897-907.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported