Eupalinolide K

CAT: 0804-HY-N2240-02Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-N2240-02Size:10 mg

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Description

Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].

CAS Number

108657-10-9

UNSPSC

12352005

Target

STAT

Type

Natural Products

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/eupalinolide-k.html

Purity

99.20

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)

Smiles

O=C(/C(C)=C/CO)O[C@H](C/C(C)=C\C[C@H](O)/C(C)=C\1)[C@](C2=C)([H])[C@]1([H])OC2=O

Molecular Formula

C20H26O6

Molecular Weight

362.42

References & Citations

Eupatorium lindleyanum

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

STAT3

Chemical Information

CID 102004412

CAS Number	108657-10-9
PubChem CID	102004412
IUPAC Name	[(3aR,4S,6Z,9S,10E,11aR)-9-hydroxy-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E)-4-hydroxy-2-methylbut-2-enoate
Molecular Formula	C20H26O6
Molecular Weight	362.4
XLogP	1.3
Topological Polar Surface Area	93.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Heavy Atom Count	26
Formal Charge	0
Complexity	684

SMILES

C/C/1=C/C[C@@H](/C(=C/[C@@H]2[C@@H]([C@H](C1)OC(=O)/C(=C/CO)/C)C(=C)C(=O)O2)/C)O

InChI

InChI=1S/C20H26O6/c1-11-5-6-15(22)13(3)10-17-18(14(4)20(24)26-17)16(9-11)25-19(23)12(2)7-8-21/h5,7,10,15-18,21-22H,4,6,8-9H2,1-3H3/b11-5-,12-7+,13-10+/t15-,16-,17+,18+/m0/s1

InChIKey

APOGLVUGPAVNAP-OPNIFLOASA-N

Chemical Structure

2D Structure

CAS: 108657-10-9

CID: 102004412

Formula: C20H26O6

MW: 362.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	362.4
XLogP3	1.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	362.17293854
Monoisotopic Mass	362.17293854
Topological Polar Surface Area	93.1 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	684
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	3
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-N0754-01	Eupalinolide A
HY-N0753-01	Eupalinolide B
HY-N8187-01	Eupalinolide O
HY-N8149-01	Eupalinolide H
HY-N8293	Eupalinolide I
HY-W700297	K-106
HY-175422	K-833
HY-N6734	K-252b
HY-N14380	Sannamycin K
HY-N14251	Melithiazole K

Alternative Products

Catalog	Name
MBS3840525-01	Eupalinolide A
CGC06783-01	Eupalinolide H
300258	Eupalinolide K
MBS3840483-01	Eupalinolide B
GTR19237153-01	Eupalinolide O
GTR19181680	Eupalinolide I

Eupalinolide K

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