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Anti-EOMES/Tbr2 Antibody

CAT: 0519-A00992Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A00992Size:100 µL
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Description
Boster Bio Anti-EOMES/Tbr2 Antibody catalog # A00992. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.
Synonyms
Eomesodermin homolog; T-box brain protein 2; T-brain-2; TBR-2; EOMES; TBR2
Gene Name
EOMES
UniProt
O95936
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human EOMES. AA range:59-108
Tissue Specificity
Expressed in CD8+ T-cells. .
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
72732 MW
Gene Name Synonym
Eomesodermin homolog
Subcellular Location
Nucleus .
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

UniProtKB · O95936

Eomesodermin homolog

EOMES_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95936
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EOMES
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7Z4I2, B7ZA51, G3XAI5, Q8TAZ2, Q9UPM7
Protein keywords

Molecular function

ActivatorDevelopmental proteinDNA-binding

Biological process

Adaptive immunityDifferentiationGastrulationImmunityTranscriptionTranscription regulation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome