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Rabbit Polyclonal Antibody to MPRIP

CAT: 1725-P42479-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P42479-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. UniProtKB P97434Surks H.K., J. Biol. Chem. 278:51484-51493 (2003) .Koga Y., J. Biol. Chem. 280:4983-4991 (2005) .Inazawa J., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Product Name Alternative
Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip
Swiss Prot
Q6WCQ1
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from internal of human MPRIP.
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
MPRIP
Bands Size
117kDa

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