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Rabbit Polyclonal Antibody to TOB1 (Phospho-Ser164)

CAT: 1725-P40515-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P40515-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.Matsuda S., Oncogene 12:705-713 (1996) Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databasesKalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
Product Name Alternative
TOB; Transducer of erbB-2 1
Swiss Prot
P50616
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around phosphorylation site of Serine 164 (A-V-S (p) -P-T) derived from Human TOB1.
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide.
Antibody Type
Primary antibody
Protein Name
TOB1 (Phospho-Ser164)
Bands Size
40kDa

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