Glyoxal

• Description :

  Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs) . Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2].

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H317, H319, H332, H341

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Smiles :

  O=CC=O

• Molecular Formula :

  C2H2O2

• Molecular Weight :

  58.04

• Precautions :

  H315, H317, H319, H332, H341

• References & Citations :

  [1]Shangari N, O'Brien PJ. The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol. 2004 Oct 1;68 (7) :1433-42.|[2]Lange JN, et al. Glyoxal formation and its role in endogenous oxalate synthesis. Adv Urol. 2012;2012:819202.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature, keep dry and cool

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [107-22-2]